I've changed port default to 99, and then use ssh stop and restart nginx
Stoping nginx... done
Starting nginx... done
[root@vultr ~]# service nginx status
nginx (pid 32748 3112 3111 3110 3109) already running.
But when I access to URL with a new port, my website is still down.
And I use nginxmanage in backend AApanel to restart

My website works right, but my other app use port 80 will not work.